
Team
Bon-Kyoung Koo
1996-2000
Bachelor Student at Dept. of Life Sci., POSTECH, S. Korea
2000-2002
Master student at Div. of Mol. and Life Sci., POSTECH, S. Korea
2002-2006
Ph.D. student at Div. of Mol. and Life Sci., POSTECH, South Korea
2006-2009
Post-Doc in Prof. Young-Yun Kong’s lab, POSTECH and Seoul National University
2009-2013
Post-Doc in Prof. Hans Clevers’ lab at Hubrecht Institute, KNAW, The Netherlands
2013-2017
Group Leader at the Cambridge Stem Cell Institute, University of Cambridge, UK
2017-2023
Group Leader at the Institute of Molecular Biotechnology (IMBA), Vienna, Austria
2021-2023
Associate Director at the Center for Genome Engineering, IBS, Daejeon, S. Korea
2023-Present
Director at the Center for Genome Engineering, IBS, Daejeon, S. Korea

Team
Ji-Hye Yun

Team
Heetak Lee
2022 – Present
Senior Researcher, CGE
2020 – 2021
Post-doc, IMBA (Advisor: Bon-Kyoung Koo)
2013 – 2020
Ph.D. POSTECH (Advisor: Sanguk Kim)
Team
Eunae Sandra Cho
2023~present
Adjunct Scholar, Team leader, Center for Genome Engineering, Institute for Basic Science
2018~present
Assistant professor, Department of Oral Pathology, Yonsei University College of Dentistry
2017~2018
Basic research professor, Department of Oral Pathology, Yonsei University College of Dentistry
2016~2017
Fellow, Department of Oral Pathology, Yonsei University College of Dentistry

Host-virus interactions are complex processes that span binding to cells, entry, dissemination, and finally lytic or latent infection. During infection, host innate immune system restricts viral replication. However, mechanisms underlying viral propagation out of the host surveillance remain unclear.
Our research goal is to understand the molecular basis of virus latency establishment and how it plays a critical role in cellular immune evasion and/or viral reactivation. In addition, we are interested in understanding the role of “the endogenous parasites”, retroelements, in host-virus interaction and innate immunity.

High-resolution mapping of RNA-protein interactions & ultrasensitive and super-resolution proximity labeling proteomics

Our laboratory is working on innovative solutions to combat the degenerative diseases of the musculoskeletal system that inevitably come with aging.

Hyeshik Chang develops and applies transcriptome profiling technologies to explore new RNA regulation mechanisms. His team has specialty in modifying high-throughput sequencing techniques and employing machine learning to identify patterns within large data sets.